The article below may contain offensive and/or incorrect content.
Objective: The purpose of the present study was to deepen our understanding of attention (a core cognitive ability) in Rett syndrome (RTT), an x-linked neurodevelopmental disorder caused by mutations in the MECP2 gene. We focused on 2 key aspects of visual orienting–shifting and disengaging attention–both of which are critical for exploring the visual world. We used gaze-based measures and eye-tracking technology to minimize demands on the limited verbal and motor abilities associated with RTT. Method: Shifting and disengaging attention were examined in 31 children (2â€"12 years) with Rett Syndrome (RTT) and 31 age-matched typically developing (TD) controls. Using the gap-overlap paradigm, the frequency and speed of shifting attention from a central to peripheral target were compared on Baseline trials, where the central stimulus disappears as the peripheral target appears, and Overlap trials, where the central stimulus remains, thus requiring disengagement. Results: Our findings revealed that children with RTT had more "sticky fixations" (p < .001). That is, they had fewer saccades to the peripheral target than TD children, and this was true on both baseline (77% vs. 95%), and overlap trials (63% vs. 90%). The younger children in the RTT group also had slower saccadic RTs (SRTs) than their TD counterparts (p = .04). Within the RTT group, SRTs correlated with symptom severity. Surprisingly, disengagement cost (the relative difference between gap and overlap SRTs) did not differ across groups. Conclusion: Our results suggest that children with Rett have difficulty shifting attention and, to a lesser extent, disengaging attention, whereas with other disorders, problems with disengagement are paramount. (PsycINFO Database Record (c) 2019 APA, all rights reserved)





Parent Site

Departments
Authors
Libraries
Current Articles
- Article Correctness Is Author's Responsibility: Scientific Meeting » Workshop: Gene-based Therapeutics for Rare Genetic Neurodevelopmental Psychiatric Disorders
- Article Correctness Is Author's Responsibility: Guiding gender-atypical kids through puberty
- Article Correctness Is Author's Responsibility: Pandemic worsens child mental health crisis
- Article Correctness Is Author's Responsibility: Being heard is more important to some people than following COVID-19 regulations
- Article Correctness Is Author's Responsibility: Workaholics at a greater risk of depression
- Article Correctness Is Author's Responsibility: Can kids have seasonal affective disorder?
- Article Correctness Is Author's Responsibility: Video » NIMH Expert Dr. Krystal Lewis Discusses Managing Stress & Anxiety
- Article Correctness Is Author's Responsibility: Scientific Meeting » NIMH Livestream Event: Managing Stress and Anxiety
- Article Correctness Is Author's Responsibility: A third of Americans don't see systemic racism as a barrier to good health
- Article Correctness Is Author's Responsibility: The challenge of pandemic fatigue is hitting people hard
- Article Correctness Is Author's Responsibility: How and why to take a break from the news
- Article Correctness Is Author's Responsibility: What brain imaging tells us about decluttering our minds
- Article Correctness Is Author's Responsibility: Blog Post » Showing Support for Basic Researchers
- Article Correctness Is Author's Responsibility: How to reduce news-related stress for better mental health
- Article Correctness Is Author's Responsibility: Five myths about loneliness
- Article Correctness Is Author's Responsibility: How to help someone struggling with suicidal ideation
- Article Correctness Is Author's Responsibility: Better sleep hygiene is crucial when you're anxious
- Article Correctness Is Author's Responsibility: How to remotivate kids for more distance learning
- Article Correctness Is Author's Responsibility: How to set goals you’ll actually achieve
- Article Correctness Is Author's Responsibility: To 'keep sharp' this year, keep learning